Lake Druksiai is located in the northeastern part of Lithuanian Republic on the borderline between Lithuania and Belarus. Its northern part belongs to Belarus, where the lake is called Lake Drisvyaty. It belongs to the River Desna system spreading over the eastern slope of Baltic Hills and the lowland of Desna.

The landscape of the region is characterized by the relief formed by glacial action, consisting of picturesque mountain ridges, ravines, lakes and plains as well as by pine forests and vast water-meadows. In Desna basin, the crystalline bedrock lies at a depth of 750 m, and is overlaid by thick layers of sedimentary rocks belonging to Upper Proterozoic, Cambrian Ordovician, Silurian, Devonian and Quaternary horizons. The lithological composition of Quaternary sediments (90 m thick) deposited during the three glacial periods is diverse. Moraines of clay, clay loam, carbonate sapropel, sand, mixed sand and gravel, etc. have been detected.

Since 1984, the Ignalina Nuclear Power Plant (INPP) started operation using the lake as its cooling pond. The Scientific Base was established on the northern shore in 1978. The lake is now used for power generation, irrigation and fishery, and also for cultural and everyday needs (Q).